MicrophthalmiaGenetic and Rare Diseases Information.
26/11/2007 · The combined birth prevalence of these conditions is as high as 1/33,000, with microphthalmia reported in up to 11% of blind children. Clinical description High-resolution cranial imaging, post-mortem examination and genetic studies suggest that these conditions represent a phenotypic continuum.
Anophthalmia and microphthalmia
26/11/2007 · Anophthalmia and microphthalmia describe, respectively, the absence of an eye and the presence of a small eye within the orbit. The combined birth prevalence of these conditions is up to 30 per 100,000 population, with microphthalmia reported in up to 11% of blind children.
Microphthalmia is a disorder in which one or both eyes are abnormally small, while anophthalmia is the absence of one or both eyes. These rare disorders develop during pregnancy and can be associated with other birth defects.
Microphthalmia - Genetics Home Reference - NIH
Microphthalmia is an eye abnormality that arises before birth. In this condition, one or both eyeballs are abnormally small. In some affected individuals, the eyeball may appear to be completely missing; however, even in these cases some remaining eye tissue is generally present.
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